Encara no tenim significats per a "biallelic inactivation".
1This biallelic inactivation resulted in loss of expression of MLH1 in the tumor as confirmed by immunohistochemistry.
2A-T is caused by biallelic inactivation of the ATM gene, in most cases by frameshift or nonsense mutations.
3Biallelic inactivation of BRCA1 or BRCA2 is associated with a pattern of genome-wide mutations known as signature 3.
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