Understanding the molecular basis of IRD is vital for clinical and geneticclassification of patients.
2
After reviewing the history of mitochondrial diseases, I follow a geneticclassification to discuss new developments and old conundrums.
3
These data establish the basis for a molecular geneticclassification of clear-cell renal-cell carcinoma that could influence treatment decisions in the future.
4
The RNase-A mismatch method combined with phylogenetic analysis permitted the primary geneticclassification of 33 of 35 samples from the WHO Network.
5
Therefore, we integrated copy-number alteration data from the 8 most commonly deleted genes, subordinately, with established chromosomal abnormalities to derive a 2-tier geneticclassification.