Meanings of induce ifn in anglès

Unmethylated CpG-ODN protect mice from infection with this fungal pathogen by inducing IFN-gamma.

We found that the Hu-191 virus induced IFN-β much more potently than the Edmonston strain.

The low amounts of the induced IFN-beta synergize with IFN-gamma in mounting the potent antiviral effect.

Specific palindromic sequences in synthetic oligonucleotides are required to induce IFN and augment IFN-mediated natural killer activity.

In all vaccinated but none control animals, E. ruminantium- induced IFN-gamma secretion was observed in 24 h stimulated blood.

Our results show that both extracts enhanced L. acidophilus- induced IFN-β production and slightly decreased the proinflammatory response to E. coli.

Neutralization of virus- induced IFN production by antibodies against type I and II IFNs prevented the virus-induced upregulation of HLA antigens.

The combination of anti-PD-L1 Abs and MPLA also promoted human peripheral blood pDC activation and induced IFN-a-dependent T cell activation.

Here we report that cytokines secreted by influenza A virus-infected macrophages are able to induce IFN-gamma synthesis in human T cells.

Importantly, parasite Ag- induced IFN-gamma synthesis by purified T cells from these animals could be restored by in vitro exposure to IL-12.

As the MR induces IFN expression, our data suggests the MR is involved in a positive feedback loop that controls HSV-1 infection.

Human B7-H3 was first described as a positive costimulator, most potently inducing IFN-gamma production and cellular immunity.

DNA sensing to induce IFN-β triggers host immunity to pathogens but constitutive DNA sensing can induce sustained IFN-β release that incites autoimmunity.

Conclusions: Liver B cells may play an important role in the defense against gram-negative bacterial infections by inducing IFN-gamma production from liver NK cells.

Protection against disease was associated with a moderate decrease in clonal expansion and a profound and persistent decrease in Ag- induced IFN-gamma production in vivo.

Likewise, the synergistic effect of IL-12 with the other stimuli to induce IFN-gamma was stronger than that observed in the case of GM-CSF or TNF-alpha.