Significats de mediate ee en anglès

The factors mediating EE effects on visual cortical development and plasticity are still unclear.

We have investigated whether IGF-1 is involved in mediating EE effects on the developing visual cortex.

These results show that IGF-1 is a key factor mediating EE effects on visual cortical development.

Our study thus identifies a novel mechanism by which Numb regulates endocytic sorting by mediating EE fusion.

This suggests that IGF-1 action in mediating EE effects could be exerted through the modulation of intracortical inhibitory circuitry and PNN development.