Significats de mediate modulation en anglès

Receptor- mediated modulation of ion channels generally involves G-proteins, phosphorylation, or both in combination.

Although LAP contributes to fungal degradation, the molecular mechanisms underlying LAP- mediated modulation of inflammation are unknown.

The present study investigates whether Ang II- mediated modulation of sympathetic neurotransmission is dependent on NO production in the kidney.

Non-cardiac ATGL- mediated modulation of the cardiac lipidome may play an important role in the pathogenesis of chronic heart failure.

IR- mediated modulation on propagating and locally evoked APs should be considered as two separate models for axonal and somatic modulations.

The NT- mediated modulation showed no desensitization and was antagonized by the NT1 antagonists SR48692 and SR142948.

Collectively, the observations provide biologically relevant insights into KLF2- mediated modulation of these inflammatory processes that could potentially be manipulated for therapeutic gain.

MiRNA- mediated modulation of the inflammatory response post-stenting may have therapeutic potential to accelerate wound healing and enhance the clinical efficacy of stenting.

Our results indicate that nutrients may exert a direct effect on long bone growth via mTOR- mediated modulation of chondrogenesis at the growth plate.

The presented data support a novel pathway for pathogen-accelerated atherosclerosis, which relies on oxidized low-density lipoprotein- mediated modulation of anti-inflammatory response to TLR ligands.

The findings suggest that ATRAP- mediated modulation of sodium handling in renal distal tubules could be a target of interest in salt-sensitive blood pressure regulation.

Voltage-dependent facilitation of ICa and block of dopamine inhibition after preincubation with a Gβγ-blocking peptide suggested involvement of Gβγ proteins in the D1R- mediated modulation.

Viral restoration of TGR5 in the nucleus accumbens of TGR5 knockout animals is sufficient to restore cocaine reward, centrally localizing this TGR5- mediated modulation.