Significats de protein domain en anglès

Phylogenetic tree and conserved protein domain analyses showed sequence conservation and divergence.

We calibrate a scoring system from protein domain alignments to score mutations and their target loci.

Metazoan evolution involves increasing protein domain complexity, but how this relates to control of biological decisions remains uncertain.

We analyzed the protein domain organization of 67 eukaryotic species including four oomycete and five fungal plant pathogens.

The optimal binding motif(s) of a protein domain is identified by screening a combinatorial peptide library.

The analysis of the core protein domain organization revealed that all chondroitin attachment sites are located in unstructured regions.

It is proposed that VbsS activates L-N5-hydroxyornithine via covalent attachment as an acyl thioester to a peptidyl carrier protein domain.

We show here that Mac1p DNA binding required an intact N-terminal protein domain that includes a likely zinc finger motif.

CANDID can use information from publications, protein domain descriptions, cross-species conservation measures, gene expression profiles and protein-protein interactions in its analysis.

FANTOM5 data provide cell-type-specific digital expression of human protein -coding genes and the SUPERFAMILY resource is used to provide protein domain annotation.

Summary: MaxBench is a web-based system available for evaluating the results of sequence and structure comparison methods, based on the SCOP protein domain classification.

Conclusions: By integrating a variety of biologically relevant features to predict domain targets, we demonstrated a notably improved prediction of modular protein domain targets.

Finally, our analysis reveals the disposition of the N-terminal segment of Msm σA, which may comprise an intrinsically disordered protein domain unique to mycobacteria.

The peptide sequence RPNVELCRD, or a variant of it, is a prominent feature of tektins and is likely to form a functionally important protein domain.

The number of protein domain sequences included has doubled from 15 190 to 30 867, and additional databases have been added.

Evaluation of targeted phylogenies and protein domain organization revealed that the "unique" Sia biosynthetic pathway of animals was instead a much more ancient innovation.