Significats de restrict t-cell en anglès

Among panels of vaccinia- restricted T-cell clones, most were DR-restricted but rare DQ-restricted clones were also recovered.

HLA molecules that restrict T-cell responses are one of the most polymorphic host factors in humans.

In particular, vaccines using defined tumor-associated peptide epitopes elicit only a restricted T-cell repertoire in a minority of patients.

FVFTLTVPS was identified as the core sequence of a new major histocompatibility complex class II- restricted T-cell epitope of influenza virus matrix protein.

Results: Patients with DQ2.2 and no other risk alleles had gluten-reactive T cells that did not respond to the common DQ2.5- restricted T-cell epitopes.

Here we report studies on the influence of aa substitutions in the DQ beta 1*0201 chain on DQ2- restricted T-cell recognition of gluten antigens.