Significats de transcriptional activation en anglès

The former was a transcriptional activation domain in the absence of c-Jun.

We showed that different promoter regions took part in transcriptional activation.

Dimerization was an absolute requirement for constitutive AR-V DNA binding and transcriptional activation.

Conversely, knockdown of LSD1 protein levels abrogates androgen-induced transcriptional activation and cell proliferation.

The region is also required for transcriptional activation, suggesting that the functions are linked.

In summary, there may be a significant contribution of transcriptional activation to multi-drug resistance.

We investigated the molecular mechanism by which TGF-beta inhibits transcriptional activation mediated by AR.

Like human STAT1beta, it lacks the C-terminus acting as transcriptional activation domain in mammals.

Our results suggest that transcriptional activation may be involved in transformation by myb gene products.

Ischemia or stimulation also leads to protooncogene transcriptional activation.

However, despite the importance of transcriptional activation in both processes, the target gene requirements are different.

STAT3-controlled transcriptional activation with yet unknown cell-specific functional consequences seems to be involved in this process.

It has been shown that transcriptional activation of AR is regulated through interaction with various co-factors.

The functions of each of these proteins were experimentally addressed using co-transformation and transcriptional activation assays.

Existing evidence indicates nitroalkenes support posttranslational protein modifications and transcriptional activation that promote the resolution of inflammation.

Wnt-induced formation of nuclear Tcf-beta-catenin complexes promotes transcriptional activation of target genes involved in cell fate decisions.