Significats de transcriptional enhancer en anglès

In this study, we identified a transcriptional enhancer from the mouse mef2c gene sufficient to direct expression to the vascular endothelium in transgenic embryos.

The activity of this segment was mapped to the major splice donor and sequences overlapping with, but functionally distinct from, a previously described transcriptional enhancer.

TEAD4 is a member of transcriptional enhancer factor (TEF) family of transcription factors and plays a pivotal role in regulating embryonic development and muscle regeneration.

Developmental gene expression patterns are orchestrated by thousands of distant-acting transcriptional enhancers.

The identification of transcriptional enhancers has proven rather difficult by conventional experimental approaches.

In this review we discuss how recent epigenomic studies have provided insights into the function of transcriptional enhancers.

Super-enhancers (SEs) are large clusters of transcriptional enhancers that are co-occupied by multiple lineage-specific transcription factors driving expression of genes that define cell identity.