Meanings of apical extrusion in English

IEC are terminated by apical extrusion-or shedding-from the intestinal epithelial monolayer into the gut lumen.

We also observe apical extrusion of Src-transformed cells in the enveloping layer of zebrafish gastrula embryos.

Importantly, activation of these signalling pathways depends on the presence of surrounding normal cells and plays a crucial role in apical extrusion of Src cells.

We also demonstrate that E-cadherin knockdown in normal cells surrounding Ras(V12) cells reduces the frequency of apical extrusion, while promoting basal protrusion formation and invasion.