Small endogenous vesicles calledexosomes are beginning to be explored as drug delivery vehicles.
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In this study, we demonstrate that various types of macrophages internalize microvesicles, calledexosomes, secreted by breast cancer and non-cancerous cell lines.
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Prions can infect recipient cells when packaged into endosome-derived nanoparticles calledexosomes, which are present in biological fluids such as blood, urine, and saliva.
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Electron microscopy studies revealed the presence in this fraction of small vesicles calledexosomes with a heterogeneous size from 60 to 100 nm of diameter.