1
Conformational studies showed that multivalent assembly enhanced the alpha-helical content of the peptide.
2
Protein-glycan interactions are typically low affinity, requiring multivalent interactions to achieve a biological effect.
3
Thus, the enzyme has potential as a component of a multivalent vaccine against schistosomiasis.
4
These results have implications for the design of multivalent vaccines.
5
Furthermore, to reduce the burden of vaccination, the development of multivalent vaccines is highly desirable.
6
Like Chekhov's gun, the unexploded bomb starts to weigh on the home in multivalent ways.
7
Results: In the absence of serum, all CL-DNA complexes of custom-synthesized multivalent lipids show high TE.
8
The data support the use of the GMMA technology for the development of intramuscular multivalent Shigella vaccines.
9
Our study suggests that multivalent vaccines may be more suitable in this setting, especially for HIV-infected individuals.
10
The use of such multivalent vaccines did not show overt immune interference in comparison with monovalent vaccines.
11
Here, we estimate that multivalent interactions for WT Syk improve cis-oriented binding by three orders of magnitude.
12
Proteasomal digestion studies and mass spectrometry analysis showed cleavage of the multivalent construct to generate the individual epitopes.
13
The most important advantage of loligomers is the multivalent presentation of targeting signals resulting from a tentacular arrangement.
14
Our work demonstrates the importance of avidity via multivalent anionic lipid interactions in the spatial control of GTPase activation.
15
Our data demonstrate that this multivalent P. haemolytica vaccine is safe and stimulates marked antibody responses in bighorn sheep.
16
Both monoclonal T cell-specific antibodies and multivalent major histocompatibility complex proteins are used as diagnostic reagents for T cell-mediated diseases.