Meanings of pharmacological modulation in English

Therefore, this cellular mechanism represents an attractive target for pharmacological modulation.

Glutamine offers pharmacological modulation of injury through clinically acceptable preconditioning.

These data lead to the conclusion that pharmacological modulation of GPR17 has therapeutic potential to treat obesity.

Without reliable structural data, the mechanistic basis for the pharmacological modulation of GABA A receptors remains largely unknown.

Importantly, neuroinflammation promotes disease progression in these models, suggesting that pharmacological modulation of inflammation might ameliorate disease outcome.

In the present review, we discuss sphingolipid metabolism in cancer, and specifically the potential for pharmacological modulation using ASM.

Effects of pharmacological modulation of acetate transport or acetate incorporation into lipids on MMC cell survival and viability were assessed.

We demonstrate the viability of a controlled ex vivo model of intact porcine and human hearts for electrophysiology with pharmacological modulation.

This model could be useful in the study of wound healing and pharmacological modulation after LASIK in an animal with Bowman's layer.

Taken together, pharmacological modulation and non-pharmacological modulation of reconsolidation and extinction are promising approaches to regulate drug reward memory and prevent relapse.

However, further information is needed before pharmacological modulation of the endocannabinoid system may prove useful for therapeutic intervention in stroke and related ischemic syndromes.

Accordingly, the hSK2 protein is a potential target for pharmacological modulation of liver transport and metabolism through effects on membrane K(+) permeability.

This was tested using islets with an inducible-expression mutation which renders defined numbers of cells electrically inactive, together with pharmacological modulation of electrical activity.

These data suggest that SOD-1 mediates CCR5 activation by CCL5 and that pharmacological modulation of SOD-1 may be beneficial to CCR5-associated diseases.

Pharmacological modulation of these feedback loops may alleviate deficient insulin release in diabetes.

Pharmacological modulation of glial activity with ibudilast decreased some subjective ratings of opioid withdrawal symptoms.