Exploring the factory presets was both flat out fun and acted as a springboard for producing further ideas for songwriting.

Indeed each governance change risks producing further ructions, for example the disruptions that have resulted from Iran's policy trajectory since 1979.

Casey said: "I am really looking forward to working with our group of talented lightweights and producing further international success."

Following the initial diversity generated by V(D)J recombination, somatic hypermutation is the principal mechanism for producing further antibody repertoire diversity in antigen-experienced B cells.