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Disease characteristic in which the disease resists treatment.
intractable disease
1
Conclusion: SLE patients with delayed treatment and
refractory
disease
have poorer prognosis.
2
The outcome of patients with multiply relapsed or cisplatin-
refractory
disease
remains particularly poor.
3
Fifteen were sensitive relapses of poor prognosis, 11 initially
refractory
disease
.
4
In testicular cancer, paclitaxel has initially been tested in patients with cisplatin-
refractory
disease
.
5
The impact is greater in patients with greater disease severity, comorbidities, or
refractory
disease
.
6
We assessed the efficacy and safety of ibrutinib in a population with rituximab-
refractory
disease
.
7
Patients with
refractory
disease
did not benefit from high-dose chemotherapy.
8
Patients and methods: Patients were eligible at first relapse or first designation of
refractory
disease
.
9
While corticosteroids and disease-modifying anti-rheumatic drugs improve outcomes, there remain children who experience
refractory
disease
.
10
Newer therapies are needed to improve the outcomes of patients with poor-risk primary
refractory
disease
.
11
However, its role in the treatment of patients with primary
refractory
disease
is not well defined.
12
Further studies are needed to characterize the role of cystectomy in treatment-
refractory
disease
from radiation therapy.
13
Forty-eight patients were treated of which 71% had
refractory
disease
.
14
Vitiligo is a common and
refractory
disease
worldwide.
15
Although cisplatin is used routinely in treating bladder cancer,
refractory
disease
remains lethal for many patients.
16
In prostate cancer, estramustine phosphate is widely used as palliative treatment for patients with hormone-
refractory
disease
.
refractory
disease
refractory