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Meanings of throw out of kilter in English

Throw into great confusion or disorder.

Usage of throw out of kilter in English
1
However, his rhythm was thrown out of kilter by the incessant banging of the war protestors' drums.
Agent 6
2
With Sakharov's death, that vast part of the world whose center is Moscow was thrown out of kilter.
The new yorker
3
His team identified networks of hundreds of genes that appear to be thrown out of kilter when mice are fed a high-fat diet.
Reuters
4
Because the Government does not want to get caught with its figures being thrown out of kilter by a no-deal Bre(...)
The Irish Times