Genetically encodedredox probes enable the functional analysis of individual proteins in cellular redox homeostasis.
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The development of genetically encodedredox biosensors offers a promising new way to investigate redox biology.
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Recent advances to quantitatively describe defined redox changes include the application of genetically encodedredox biosensors.
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These studies identify the role of ROS in pathogenesis associated with mitochondrial disease and demonstrate the utility of genetically encodedredox sensors in Drosophila.
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The most advanced and promising tools for specific, quantitative, dynamic and compartment-specific observations are genetically encodedredox probes derived from green fluorescent protein (GFP).