Central nervous system disease.
1
However, the mechanism by which TDP-43 mutations lead to neurodegeneration is unclear.
2
There is urgent need to overcome such deleterious effects of age-related neurodegeneration.
3
This study aimed to investigate the mechanisms underlying HCV core protein-mediated neurodegeneration.
4
The mechanism of neurodegeneration caused by beta-amyloid in Alzheimer disease is controversial.
5
Certain mutations can cause proteins to accumulate in neurons, leading to neurodegeneration.
6
However, the role of specific HDACs in cognition and neurodegeneration remains poorly understood.
7
Histopathological and radiological analysis revealed that neurodegeneration occurs early in the disease course.
8
Despite extensive efforts, the precise role of a-synuclein aggregation in neurodegeneration remains unclear.
9
The association with rs794185 was highly significant in the group with high neurodegeneration.
10
This predicts that measures of neurodegeneration will correlate most strongly between interconnected structures.
11
Recent trends demonstrate links between OSA and AD-biomarkers of neurodegeneration across all age-groups.
12
The function of PERK tauopathy variants and their effects on neurodegeneration are unknown.
13
This IN Tat model of neuroinflammation may be useful to study HIV-1-induced neurodegeneration.
14
Both classic and milder phenotypes develop progressive neurodegeneration in early adulthood.
15
Specific molecular mechanisms by which mHtt elicits neurodegeneration have been hard to determine.
16
We report two sisters who presented with neurodegeneration triggered by infections.
