Significados de post-mortem brain en inglés

Six patients had post-mortem brain analysis available for assessment of neuropathological findings associated with prion disease.

Several studies have reported whole-genome expression profiling in post-mortem brain but reported concordance between these analyses is lacking.

Both in-vivo models and post-mortem brain samples of individuals with AD have commonly shown hyperactivation of the pathway.

We performed a cross-tissue analysis of methylomic variation in AD using samples from four independent human post-mortem brain cohorts.

Using post-mortem brain transcriptomic data, we confirmed alterations in these cells, even at the earliest stages of disease progression.

Detailed analysis of human post-mortem brain tissue revealed a selective loss of CLDN3 at the choroid plexus in MS patients compared to control tissues.

Importantly, this hypothesis was further supported by data obtained from human post-mortem brain material derived from patients with MSA and dementia with Lewy bodies.

To confirm their anatomical findings, and try to establish how these size differences might occur, the researchers examined post-mortem brain tissue obtained from 10 adults.

This retrospective study utilized archived post-mortem brain tissues obtained from 35 individuals enrolled in a longitudinal study as part of the California NeuroAIDS Tissue Network.

Using post-mortem brain tissue from 12 CADASIL patients and 10 age-matched controls, we found that WMLs are heterogeneous, and that BBB leakage reflects the heterogeneity.

Post-mortem brain tissue was obtained from a group of patients with well documented clinical histories of affective disorder.

Furthermore, expression of 14-3-3 genes was altered in post-mortem brains of ASD and schizophrenia patients.