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Bacillus anthracis is a spore-forming, Gram-positive pathogen and the causative agent of anthraxdisease.
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Infection with Bacillus anthracsis spores induces an acute anthraxdisease that can cause casualties and death in untreated cases.
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Subcutaneous delivery of Sap inhibitory nanobodies cleared B. anthracis infection and prevented lethality in a mouse model of anthraxdisease.
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The lethal anthraxdisease is caused by spores of the gram-positive Bacillus anthracis, a member of the cereus group of bacilli.
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The FBI is investigating the death of a British-born journalist in the US after he was exposed to anthraxdisease at his workplace.
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These results indicate that a combined treatment of antibiotics together with a PA-based vaccine could provide long-term protection to prevent recurrence of anthraxdisease.