Offline quantitative image analyses were performed to assess the average and minimum lumen area (LA).

The same results were obtained at the minimum lumen site and in the subgroup of patients who had acute coronary syndromes.

No significant differences were observed in terms of flow velocity, percent diameter stenosis, minimum lumen diameter, and reference diameter between LAD and LCx.

The area under the receiver-operating characteristic curve was 0.93 for FFRQCA, 0.73 for minimum lumen area, and 0.65 for percent diameter stenosis.