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1
Methods: Analysis of patient-level data from 3 large surgical
randomized
controlled
trials.
2
Further studies, particularly
randomized
controlled
trials, are needed to confirm these benefits.
3
Results: The majority of the eleven eligible studies were
randomized
controlled
trials.
4
Results: We identified eight
randomized
controlled
trials that satisfied all inclusion criteria.
5
Further investigation with
randomized
controlled
trials should be considered in future studies.
6
These
randomized
controlled
trials are considered the gold standard of medical research.
7
Methods: We designed a multi-center,
randomized
controlled
trial with three follow-up points.
8
Material and methods: The study was a prospective
randomized
controlled
clinical study.
9
Methods: This was a follow-up study of two large
randomized
controlled
trials.
10
These findings need to be confirmed in a prospective
randomized
controlled
trial.
11
This study was conducted within a
randomized
controlled
trial across 8 sites.
12
This patient subgroup should ideally be evaluated in future
randomized
controlled
trials.
13
Seventeen were
randomized
controlled
studies comparing Proton Beam Therapy with current practice.
14
It is important to confirm these observations in a
randomized
controlled
trial.
15
Data for meta-analyses were extracted from
randomized
controlled
trials meeting meta-analysis criteria.
16
The study was set up as a single blind
randomized
controlled
trial.