However, the optimal dosing regimen of the aminoglycoside remains to be elucidated.

The penicillin-aminoglycoside combination is recommended for the treatment of systemic enterococcal infections.

A consensus set of phenotypic criteria for aminoglycoside-induced nephrotoxicity have recently been published.

No gene known to provide aminoglycoside resistance was seen in St-10.

Four of the seven drugs inhibited aminoglycoside uptake, based on Texas-Red-conjugated gentamicin uptake.

Amphiphilic aminoglycoside derivatives are potential new antimicrobial agents mostly developed to fight resistant bacteria.

CNE patients who received aminoglycoside therapy survived more frequently than CNE patients without this therapy.

These findings identify a previously undescribed genomic island that confers resistance to multiple aminoglycoside antibiotics.

In addition, heat shock results in significant inhibition of both cisplatin- and aminoglycoside-induced hair cell death.

Patients who received only an aminoglycoside had the poorest response rate among those who received appropriate therapy.

Monotherapy was used for treatment of complicated urinary tract infections, usually with an aminoglycoside or a polymyxin.

A clinical database of inborn patients of all gestations was analyzed for association between sPDA and aminoglycoside treatment.

We recently reported preliminary results from screening a small-molecule library for compounds that inhibit aminoglycoside-induced hair cell death.

Furthermore, we provide the first evidence of stress granule formation in mammalian hair cells in-vivo triggered by aminoglycoside treatment.

Hair cells are sensitive to death from exposure to therapeutic drugs with ototoxic side effects, including aminoglycoside antibiotics and cisplatin.

In conclusion, AKI was frequent among ICU patients receiving an aminoglycoside, and it was associated with a high rate of mortality.