When ingested, strychnine causes muscular convulsions before death through asphyxia.

The constant nerve irritation causes muscular contraction, consequently circulation is interfered with, producing a condition of engorgement.

Conditional deletion of LAP1 from striated muscle causes muscular dystrophy; this pathology is worsened in the absence of emerin.

If the reader wishes to give prominence to a thought, the effort put forth causes muscular tension, resulting in a higher pitch.