Usage of "gene deletion"

A mutation in which a part of a chromosome or a sequence of DNA is missing.

Использование термина gene deletion на английском

A dual guide approach improved gene deletion efficacy in both cell types. 
 Pubmed 

CHOP gene deletion in SCs decreased cell death in response to TNF-a. 
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Quantitative polymerase chain reaction indicated total WASP gene deletion in the proband. 
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Aromatase gene deletion in female mice exacerbates ischemic brain damage after stroke. 
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In addition, essential genes were predicted via single gene deletion studies. 
 Pubmed 

Gao was specifically inactivated in pancreatic progenitor cells by pancreatic cell-specific gene deletion. 
 Pubmed 

Lrh-1 gene deletion attenuates cancer cell metabolism in hepatocytes through mitochondrial glutamine processing. 
 Pubmed 

Determining the effect of gene deletion is a fundamental approach to understanding gene function. 
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The specific inhibitors and gene deletion technologies were used to address the molecular mechanisms. 
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CLIC4 gene deletion markedly attenuated the development of chronic hypoxia-induced pulmonary hypertension in mice. 
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In this study, we used gene deletion and complement methods to confirm its putative functions. 
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Conclusion: NOS2 gene deletion did not affect the inflammatory responses, but reduced the cartilage degradation. 
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Targeted gene deletion in the producer resulted in a 90% reduced diaminopentane secretion. 
 Pubmed 

Methods: We studied a twin pair with an exon 4 gene deletion in the PGRN gene. 
 Pubmed 

Recently, gene deletion revealed a predominant role of NPR-B in endochondral ossification and development of female reproductive organs. 
 Pubmed 

Thus, our findings show that ubiquitous CSF-1 gene deletion using a Cre-based system recapitulates the expected osteopetrotic phenotype. 
 Pubmed 

Значения термина gene deletion на английском