Meanings of have synchronous in английском

The prognostic value of KRAS in metastatic disease, specifically according to whether patients have synchronous or metachronous disease at presentation, is less understood.

Three patients had synchronous tumors in the ovary and appendix.

Thirty seven patients had synchronous hepatic vein occlusion.

Four patients had synchronous non-ANEN malignancies.

Local failure as a manifestation of initial relapse occurred in only three patients (15%), each having synchronous distant failure.

Three patients had tumors in the cerebral hemisphere, whereas one patient had synchronous double tumors in the cerebral hemisphere and posterior fossa.

Sixty-five percent of patients had synchronous metastatic disease at diagnosis, while 35% of the patients had received adjuvant chemotherapy after radical surgery.

Five patients survived for more than 3 years without recurrence, 3 of whom had synchronous metastases resected at the time of gastrectomy.