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Значения термина modifier gene на английском

A gene that modifies the effect produced by another gene.

Использование термина modifier gene на английском
1
Our study reveals Nrf2 as a novel modifier gene of sepsis that determines survival by mounting an appropriate innate immune response.
Pubmed
2
Here we show that the PKD1 gene can act as a disease causing and a disease modifier gene in ADPKD patients.
Pubmed
3
The estrogen metabolizing gene CYP1B1 is a strong candidate as a modifier gene in female PAH patients.
Pubmed
4
HP twins study suggests that modifier genes influence severity but not penetrance.
Pubmed
5
This finding suggests that modifier genes contribute to FPAH clinical expression.
Pubmed
6
Objectives: We intended to identify and pharmaceutically target BMPR2 modifier genes to improve PAH.
Pubmed
7
In this study, we evaluated the putative role of variants in many candidate modifier genes.
Pubmed
8
This review will summarize the methods and results thus far in the identification of atherosclerosis- modifier genes.
Pubmed
9
Incomplete penetrance suggests the existence of modifier genes.
Pubmed
10
However, patients present with wide clinical heterogeneity, suggesting that modifier genes play a role in determining severity.
Pubmed
11
Our results also highlight the BMP regulation pathway as a good candidate for identification of new modifier genes.
Pubmed
12
Family history data are critical in the study of hereditary cancer syndromes and the identification of cancer modifier genes.
Pubmed
13
However, this does not explain the phenotypic variability, which is likely modulated by environmental factors, modifier genes or age-dependent expression.
Pubmed
14
We propose a model of how HbF modifier genes and disease pathology interact to shape HbF levels measured in patients.
Pubmed
15
A genome scan of the backcross to FVB suggests that one or more modifier genes are present on chromosome 5.
Pubmed
16
With the exception of one mild missense DAX1 mutation, genotype-phenotype correlations have been elusive, suggesting an important role for modifier genes.
Pubmed