Significats de aberrant dna en anglès

Aberrant DNA methylation is a key feature of breast carcinoma.

Aberrant DNA methylation patterns may be the earliest somatic genome changes in prostate cancer.

Aberrant DNA methylation is a feature of human cancer affecting gene expression and tumor phenotype.

Aberrant DNA methylation is implicated in smoking-related lung cancer.

Previously characterized MPS1 mutants fail in both functions, leading to aberrant DNA segregation with lethal consequences.

This finding helps to explain how aberrant DNA structures in the genome induce ATR-dependent signaling processes.

Aberrant DNA methylation causes silencing of tumor suppressor genes and promotes chromosomal instability in human cancers.

Aberrant DNA methylation contributes to the malignant phenotype in virtually all types of cancer, including myeloid leukemia.

Aberrant DNA hypermethylation of gene promoter regions has been increasingly recognized as a common molecular alteration in carcinogenesis.

Additionally, aberrant DNA methylation is a common event not only in sporadic CRC but also in Lynch syndrome CRCs.

Aberrant DNA methylation within the promoter of IL17RC in peripheral blood mononuclear cells has recently been reported in AMD.

We investigated the feasibility of detecting aberrant DNA methylation in the urine and serum samples of renal cancer patients.

Aberrant DNA methylation is believed to be important in tumorigenesis by causing either transcriptional inactivation of genes or chromosomal instability.

Colon cancer (CC) is characterized by global aberrant DNA methylation that may affect gene expression and genomic stability.

The best studied of these latter processes is heritable transcriptional repression of genes associated with aberrant DNA hypermethylation of their promoters.

We conducted a critical review to summarize the evidence regarding aberrant DNA methylation patterns as a potential diagnostic biomarker predicting progression.