Significats de acentric en anglès

Our live studies reveal that acentric chromatids segregate efficiently to opposite poles.

In humans, neocentromeres often arise in cells with gross chromosome rearrangements that rescue an acentric chromosome.

However, it is unknown whether these late-segregating acentric fragments influence NEF to ensure their inclusion in daughter nuclei.

Through live analysis, we show that acentric chromosomes induce highly localized delays in the reassembly of the nuclear envelope.

Chromosome fragments that lack centromeric DNA (structurally acentric chromosomes) are usually not inherited in mitosis and meiosis.

Here we report that these acentric mini-chromosomes bind the centromere-specific protein ZW10 and associate with the spindle poles in anaphase.

While I-CreI expression produces acentric chromosomes in the majority of neuronal stem cells, remarkably, it has no effect on adult survival.

This is especially consequential with inverted target sites, where exchange between oppositely oriented target sites on sisters will produce dicentric and acentric chromosomes.

Reduced BubR1 or Polo function results in abnormal segregation of acentric chromatids, a decrease in acentric chromosome tethering, and a great reduction in adult survival.

Acentric chromosomes often exhibit delayed but ultimately successful segregation and incorporation into daughter nuclei.

These delays result in a gap in the nuclear envelope that facilitates the inclusion of lagging acentrics into telophase daughter nuclei.

Our live studies reveal that acentric chromatids segregate efficiently to opposite poles.

In humans, neocentromeres often arise in cells with gross chromosome rearrangements that rescue an acentric chromosome.

However, it is unknown whether these late-segregating acentric fragments influence NEF to ensure their inclusion in daughter nuclei.

Through live analysis, we show that acentric chromosomes induce highly localized delays in the reassembly of the nuclear envelope.

Chromosome fragments that lack centromeric DNA (structurally acentric chromosomes) are usually not inherited in mitosis and meiosis.