Significats de acute leukemias en anglès

The role of immunotherapy in maintenance of remission in children with acute leukemias is briefly reviewed.

Findings support use of PB samples for chronic myeloid neoplasms and for acute leukemias with sufficient circulating disease.

We and others have shown that human acute leukemias are heterogeneous for the pattern of Ikaros isoform expression.

MYB is an important hematopoietic transcription factor involved in proliferation as well as differentiation and upregulated in most human acute leukemias.

Indeed, as in acute leukemias and non-hodgkins lymphoma, we believe it is no longer acceptable to consider MM a single disease entity.

In acute leukemias, BM appears to be superior to PB for monitoring measurable residual disease, even in the absence of BM excess blasts.

Purpose: To determine the safety, target inhibition, and signals of clinical activity of tipifarnib in combination with bortezomib in patients with advanced acute leukemias.

While cytogenetic and molecular aberrancies currently are accepted prognostic predictors in acute leukemias, single antigen expression and even antigenic profiles rarely impact on prognosis.

This unit will outline approaches to the molecular diagnosis of the most frequent and clinically relevant genetic alterations in acute leukemias and myeloproliferative neoplasms.

A large subset of acute leukemias and other myeloproliferative neoplasms contain specific genetic alterations, many of which are associated with unique clinical and pathologic features.

A series of translocation break points found in a subset of human acute leukemias have one of the breaks on human chromosome 11q23.