Significats de adenoviral vector en anglès

ReiThera is developing a vaccine based on a so-called non-replicating adenoviral vector.

The innate immune response to intraportally infused adenoviral vector was evaluated in rhesus monkeys.

These observations suggest the therapeutic utility of a KGF-expressing adenoviral vector for pulmonary fibrosis.

Double-strand oligonucleotide for transcription of short hairpin RNA was constructed into the adenoviral vector.

The efficacy of adenoviral vector delivery to a crushed nerve was investigated using three strategies.

We demonstrate the efficient ligand-mediated re-targeting of adenoviral vector infection to the human cancer cell line WiDr.

Two control groups of tumor-bearing mice received intratumoral injections of the control adenoviral vector dl-312 or buffer alone, respectively.

Conclusion: Our study provides insight into the host transcriptional response following transduction of an adenoviral vector into mammary epithelial cells.

The adverse effects on neurons appear to be due to the observed inflammatory response or to direct adenoviral vector toxicity.

We examined marker compound distribution and transgene expression (from a first-generation adenoviral vector) at different stages of development.

Within 24 h after intraperitoneal administration of an adenoviral vector, transduction of the reporter gene was evident in the xenografts.

We have previously shown that intrathymic delivery of IL-10 with an adenoviral vector in wild-type mice significantly improves outcome to sepsis.

We have extended our previous murine studies of CD40-CD40L in adenoviral vector-mediated immune responses to rhesus monkeys.

All 6 types can be generated in mouse tissues by an adenoviral vector expressing VEGF-A(164).

Here we report that LIGHT expression via an adenoviral vector (Ad-LIGHT) is sufficient to down regulate hepatic lipase expression in mice.

These studies establish an essential role for Fas-Fas ligand interactions in the mechanism of elimination of adenoviral vector-mediated transgene expression in the liver.