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Significats de adrenoleukodystrophy en anglès

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адренолейкодистрофия
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adrenoleucodistrofia
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adrenoleucodistrofia

X-linked adrenoleukodystrophy (X-ALD) is a peroxisomal disorder resulting in cerebral demyelination, axonal dysfunction in the spinal cord leading to spastic paraplegia, adrenal insufficiency and in some cases testicular insufficiency.

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Examples for "ald"
Examples for "ald"
1
Poorly formed aggregates and reduced levels of spores were apparent in the DZ2 aldA mutant, even after prolonged development.
Pubmed
2
These data indicate that DMSP-ald is an intermediate in DMSP biosynthesis and that the other three compounds are not.
Pubmed
3
Although different X-ALD phenotypes are recognized, little is known about their evolution.
Pubmed
4
However, the mechanisms underlying the brain damage in X-ALD are poorly known.
Pubmed
5
Watch the ALD descend into the belly of the Rosalind Franklin rover.
BBC
1
Asymptomatic, adrenomyeloneuropathy and female heterozygote patients had no significant changes in cerebral perfusion.
Pubmed
2
Unfortunately, there is no early method of distinguishing it from the more benign forms of adrenoleukodystrophy, such as adrenomyeloneuropathy.
Pubmed
3
A 39-year-old male showed rapid progression of cerebral white matter involvement after 8 years' duration of adrenomyeloneuropathy.
Pubmed
1
Multislice proton MRSI may be a suitable technique for the prediction of lesion progression on MRI in X-linked adrenoleukodystrophy.
Pubmed
2
So far PGD has been carried out for three carrier females at risk of transmitting X-linked adrenoleukodystrophy, X-linked hydrocephalus and hemophilia A.
Pubmed
3
Magnetic resonance imaging sequences such as diffusion and spectroscopy have been well studied in X-linked adrenoleukodystrophy, but no data exist on magnetic resonance perfusion imaging.
Pubmed
4
X-linked adrenoleukodystrophy is a neurodegenerative disorder affecting the myelin of the nervous system and the adrenal cortex.
Pubmed
1
Although different X-ALD phenotypes are recognized, little is known about their evolution.
Pubmed
2
However, the mechanisms underlying the brain damage in X-ALD are poorly known.
Pubmed
3
It is therefore proposed that oxidative stress may be involved in pathophysiology of X-ALD.
Pubmed
4
In this review we report a detailed analysis of all 406 X-ALD mutations currently included in the database.
Pubmed
5
Diagnostic tests should be offered to all at-risk relatives of X-ALD patients and should include members of the extended family.
Pubmed
1
Technically known as X-linked ALD, it affects boys, typically starting in childhood and killing them in two to three years.
Wired
1
Pathologic explanation of the roentgenographically identified diffuse sclerosis in ES has not been previously well documented in the medical literature.
Pubmed
Ús de adrenoleukodystrophy en anglès
1
The childhood-onset cerebral form of adrenoleukodystrophy has a devastating neurologic prognosis.
Pubmed
2
A young male patient with adrenoleukodystrophy progressed from the frontal to the parieto-occipital region was reported.
Pubmed
3
Background and purpose: Outcomes following hematopoietic stem cell transplantation for higher risk childhood-onset cerebral adrenoleukodystrophy are variable.
Pubmed
4
X-linked adrenoleukodystrophy is a neurodegenerative disorder affecting the myelin of the nervous system and the adrenal cortex.
Pubmed
5
Conclusions: Gadolinium enhancement intensity on brain MR imaging can be scored simply and reproducibly for cerebral adrenoleukodystrophy.
Pubmed
6
Conclusions: Leading enhancing edge measurements likely remain normal post-hematopoietic stem cell transplantation in cerebral adrenoleukodystrophy, suggesting local disease stabilization.
Pubmed
7
Unfortunately, there is no early method of distinguishing it from the more benign forms of adrenoleukodystrophy, such as adrenomyeloneuropathy.
Pubmed
8
Multislice proton MRSI may be a suitable technique for the prediction of lesion progression on MRI in X-linked adrenoleukodystrophy.
Pubmed
9
MR perfusion values were analyzed in the patients with cerebral adrenoleukodystrophy at each time point and compared with those in controls.
Pubmed
10
So far PGD has been carried out for three carrier females at risk of transmitting X-linked adrenoleukodystrophy, X-linked hydrocephalus and hemophilia A.
Pubmed
11
Twenty patients with different phenotypes of adrenoleukodystrophy and seven age-matched controls were evaluated between 2006 and 2011.
Pubmed
12
Accumulated experience supports the efficacy of allogenic haematopoietic stem cell transplantation in arresting the progression of childhood-onset cerebral form of adrenoleukodystrophy in early stages.
Pubmed
13
Background and purpose: Early assignment of disease progression among patients with X-linked adrenoleukodystrophy (ALD) is critical for the appropriate selection of effective therapy.
Pubmed
14
Scientists have used gene therapy to halt the progression of adrenoleukodystrophy, a fatal neurodegenerative disease caused by a single defective gene, in two seven-year-old boys.
Wired
15
Magnetic resonance imaging sequences such as diffusion and spectroscopy have been well studied in X-linked adrenoleukodystrophy, but no data exist on magnetic resonance perfusion imaging.
Pubmed
16
Evaluation of the therapy of X-linked adrenoleukodystrophy (X-ALD) is hampered by its rarity and by the striking and unpredictable variation in phenotypic expression.
Pubmed
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Translations for adrenoleukodystrophy
Adrenoleukodystrophy a través del temps