Significats de affected infants en anglès

Treatment options for these severely affected infants are constantly evolving.

Most of the affected infants die early in life, and definitive diagnosis has often been made only by post-mortem evaluation.

Harlequin ichthyosis is a congenital scaling syndrome of the skin in which affected infants have epidermal hyperkeratosis and a defective permeability barrier.

Conclusions: The identification SMA affected infants via newborn screening presents an unprecedented opportunity for achievement of maximal therapeutic benefit through the administration of treatment pre-symptomatically.

Significance: These alterations may place the affected infants at a higher risk of neurological and cardiovascular complications, which could conceivably persist throughout childhood and adulthood.

Affected infants are often macrosomic, with length above the 90th centile and large head circumference.