Significats de aggregation propensity en anglès

In addition, it increased aggregation propensity by stabilizing mature filaments against disaggregation.

AβpE3 has a higher aggregation propensity and stability and shows increased toxicity compared with full-length Aβ.

However, whether methylation stoichiometry reached levels needed to influence aggregation propensity in human brain was unknown.

Results indicated that the mutants differ from each other and from wild-type tau in their aggregation propensity.

Depending on their location within the polypeptide chain, tau missense mutations have been reported to augment aggregation propensity.

Using a reliable cell culture assay, we show that all ALS-associated mutations in SOD1 increase the inherent aggregation propensity of the protein.

The structural heterogeneity, low solubility, and high aggregation propensity of Ascl1 in aqueous buffer solutions make high-resolution studies of this protein a challenging task.

This has allowed the generation of a panel of human antibody variable heavy domains with a defined range of aggregation propensities.

Using variants of the Alzheimer's related Aβ42 peptide designed to exhibit different in vivo aggregation propensities we show here th …