Significats de anticholinergic use en anglès

Conclusions and relevance: Higher cumulative anticholinergic use is associated with an increased risk for dementia.

Objective: To examine whether cumulative anticholinergic use is associated with a higher risk for incident dementia.

Conditional logistic regression was used to analyze the association between anticholinergic use and pneumonia, adjusted for comorbidities.

Efforts to increase awareness among health care professionals and older adults about this potential medication-related risk are important to minimize anticholinergic use over time.

Measurements: The prevalence of anticholinergic use was compared in the treatment and comparison groups over a 3- to 12-month follow-up period using pharmacy claims data.

Treatment group members who received anticholinergics used those drugs concomitantly with donepezil on a mean of 28.4% of follow-up period days.