Significats de belarusian republican foundation for fundamental research en anglès

Golgi complex ultrastructure is disrupted in the ffr digestive tract.

These data indicate that ffr is required for both Golgi structure and vesicular trafficking, and ultimately lipid transport.

The zebrafish fat-free (ffr) mutation was identified in a physiological screen for genes that regulate lipid metabolism.

Through positional cloning, we have identified a causative mutation in a highly conserved and ubiquitously expressed gene within the ffr locus.

Enterocyte retention of an endosomal lipid marker in ffr larvae support the idea that altered vesicle trafficking contributes to the ffr mutant defect.