Significats de bidirectional signaling en anglès

This bidirectional signaling helps maintain tissue homeostasis.

Eph-ephrin interactions result in bidirectional signaling within both receptor- and ligand-bearing cells, with diverse consequences for cell morphology and behavior.

Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior.

Dysregulated bidirectional signaling, however, could trigger the propagation of feedback loops that can lead to the establishment of a disease state such as glaucoma.

Here we discuss the role of integrins and bidirectional signaling as they relate to the glaucomatous phenotype with special emphasis on the avβ3 integrin.

These data demonstrate that ephrin-Eph bidirectional signaling links two major molecular mechanisms for cell differentiation-onein osteoclasts and the other in osteoblasts-therebymaintaining bone homeostasis.

Bidirectional signaling along the B7-CTLA-4 coreceptor pathway enables reciprocal conditioning of T cells and dendritic cells.

Bidirectional signaling of EphB4-ephrinB2 regulates cardiovascular development.