Significats de bound ligand en anglès

Here we report the first X-ray crystal structure of a teleost IRBP, and the only structure with a bound ligand.

The presence of the electron density of the bound ligand may provide important clues on the likely function of NIF3-like proteins.

A well-defined electron density corresponding to an endogenously bound ligand of unknown identity is observed in close proximity to the metal site.

Our study, which provides the first structure of an IRBP with bound ligand, supports a potential role for fatty acids in regulating retinoid binding.

Nitrocellulose sequesters proteins and bound ligand at the site of application, whereas free ligand is mobilized by bulk movement of the solvent through capillary action.

Gas-phase activation inside the mass spectrometer removes the detergent to yield the isolated proteins with bound ligands.

A semi-automated computational procedure to assist in the identification of bound ligands from unknown electron density has been developed.

An analysis of the degree of folding of the bound ligands confirmed the general tendency of small molecules to bind in an extended conformation.