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Platypus venom C-typenatriureticpeptides and nerve growth factor do not possess lineage-specific gene duplicates.
2
The mutation conferred normal binding affinity for C-typenatriureticpeptide but no discernible ligand-induced cGMP production.
3
C-typenatriureticpeptide was one order of magnitude more potent than ANP in cGMP production in cultured aortic smooth muscle cells.
4
C-typenatriureticpeptide (CNP) is an endothelium-derived peptide that is released as a protective mechanism in response cardiovascular injury or disease.