Significats de cardiac allografts en anglès

Fibrosis is one of the major causes for impaired function of cardiac allografts.

Conclusion: Thus, inhibition of miR-21 is a novel strategy to target fibrosis development in cardiac allografts.

Conclusions: Anti-CD154 antibody markedly prolongs the survival of cardiac allografts in primates and is well tolerated.

Background: Right ventricular myocardial fatty infiltration has been observed in pediatric cardiac allografts with an associated decrease in graft life expectancy.

Taken together, our in vivo data suggest that LFA-1 deactivation is important for the formation of inflammatory lesions and rejection of cardiac allografts.

Fully mismatched cardiac allografts were transplanted into alemtuzumab treated CD52Tg mice and showed no acute rejection while untreated recipients acutely rejected their grafts.