Significats de catalytic triad en anglès

This catalytic triad is also required for acetylesterase activity in vitro.

Substitution of any of the three catalytic triad amino acids with alanine produced inactive Lpa proteins.

These residues are suggested to form a charge-transfer system similar to that formed by the catalytic triad of chymotrypsin-like proteases.

The active site contains a classical catalytic triad, and two tyrosines and a glutamic acid residue that are likely to assist in catalysis.

The motifs were found to cover functionally important sites like the catalytic triad for Serine Proteases and co-factor binding sites for Nuclear Binding Domains.

These enzymes hydrolyse their substrates by a catalytic triad, with the first step of the enzymatic reaction being the formation of a covalent enzyme-substrate ester.

We conclude that, together with Ser-16, which we have identified previously, Asp-116 and His-291 compose the catalytic triad of the enzyme.

This model predicts that Cys-110 of hGH is the active site nucleophile and forms a catalytic triad with residues His-220 and Glu-222.

In silico bioinformatics analyses predicted a central region in residues 324-684 displaying the catalytic triad and the substrate binding pocket of cysteine proteases.

Many putative venom lipases were found with incomplete catalytic triads, relatively long β9 loops, and short lids.

Movement of the loop containing the catalytically essential histidine into a conformation similar to those found in structures with fully formed catalytic triads also occurred.