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Prophylaxis with fluoroquinolones was efficacious in reducing infections caused by gram-positive bacteria.

Granulocytopenic patients are at high risk for infections caused by gram-negative bacteria mostly originating from the gastro-intestinal tract.

Telavancin is an investigational lipoglycopeptide antibiotic currently being developed for the treatment of serious infections caused by gram-positive bacteria.

Infections caused by gram-negative bacteria (GNB) resistant to multiple classes of antibiotics are increasing in many hospitals.

Mortality was significantly higher if presentation was in the 1st week of life or if sepsis was caused by gram-negative bacteria.

Objective: Multiple studies have demonstrated that daily chlorhexidine gluconate (CHG) bathing is associated with a significant reduction in infections caused by gram-positive pathogens.

The majority of infectious complications in cancer patients are caused by Gram-negative bacilli.

The vast majority (62%) of septic cases were caused by Gram-positive organisms.

The use of combination antimicrobial therapy for bacteraemia caused by Gram-negative bacilli is controversial.

Clindamycin is used for infections caused by Gram-positive and Gram-negative anaerobic pathogens and Gram-positive aerobes.

Amikacin is used for treating hospital-acquired infections caused by Gram-negative bacteria resistant to other aminoglycosides.

Thus, treatment of infections caused by Gram-positive cocci resistant to other antimicrobial drugs is a potential indication of daptomycin.

These data suggest that tedizolid could be an alternative to linezolid for the treatment of infections caused by Gram-positive organisms.