ANALYSIS: Support is strong among the new states for the EU constitution.
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Even in states with highly-developed health systems, late diagnosis remains a problem.
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This is threatening Greece today, maybe other states in Europe as well.
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However, these rules have recently met significant legal opposition in multiple states.
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Seven states posted a record number of new Covid-19 cases on Friday.
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The ID2 protein supports cancer hallmarks including the cancer stem cellstate.
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Therefore, it allows for a continuous investigation of the cellstate during stretching experiments.
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Populations of isogenic cells often respond coherently to signals, despite differences in protein abundance and cellstate.
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Our understanding of the cellular and molecular mechanisms underlying the adult neural stem cellstate remains fragmentary.
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These findings demonstrate that somatic cellstate influences requirements for reprogramming and delineate two phases in the process.
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However, how stiffness changes regulate vascular cellphenotype is not well understood.
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Rituximab treatment had no effect on the T- cellphenotype and function post-transplant.
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Lactoferrin also exerts an effect on target cells depending on the cellphenotype.
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The cone cellphenotype is sensitive to the level of rugose gene function.
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The different fractions were stimulated and the B- cellphenotype and immunoglobulin profiles analyzed.
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These associations were cell type specific and reflected the cell'sphysiologicalstate.
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We also conducted association analyses relating individual insertions to a variety of cellularphenotypes.
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The cellularphenotypes of the neoplasms and the corresponding background intestinal metaplasia were also determined.
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Background: Genes present in only certain strains of a bacterial species can strongly affect cellularphenotypes and evolutionary potentials.
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These cellularphenotypes occurred in the absence of alterations in cell proliferation during cortical differentiation, differing from previous studies.
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During fetal and postnatal development, the human brain generates 160 billion neuronal and glial cells, each with precise cellularphenotypes.
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These associations were celltype specific and reflected the cell's physiological state.
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Recent evidence suggests that stochasticism is important for generating celltype diversity.
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Researchers can also transform one celltype directly into another celltype.
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This difference was caused by celltype-specific expression of different ABC transporters.
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Comparison with lung model systems revealed distinct subtype to celltype correspondence.
Ús de cell states en anglès
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Pluripotency is increasingly recognized as a spectrum of cellstates defined by their growth conditions.
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Future studies should reveal the molecular basis for the differences in activities between the different cellstates.
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Such large distributions complicate the statistical evaluation of pharmacological treatments and the comparison of different cellstates.
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Our work highlights the superior power of proteome profiles to study protein complexes and their variants across cellstates.
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Second, we define quantitative measures of dynamical modularity, namely that global cellstates are discrete combinations of switch-level phenotypes.
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Single- cell transcriptomics has transformed our ability to characterize cellstates, but deep biological understanding requires more than a taxonomic listing of clusters.
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Modifications of DNA cytosine bases and histone posttranslational modifications play key roles in the control of gene expression and specification of cellstates.
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We demonstrate that compositional signatures of variable protein complexes have discriminative power beyond individual cellstates and can distinguish cancer cells from healthy ones.
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The need to derive and culture diverse cell or tissue types in vitro has prompted investigations on how changes in culture conditions affect cellstates.
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The complex interrelationships between pluripotency and chromatin factors are illustrated by X chromosome inactivation, regulatory control by noncoding RNAs, and environmental influences on cellstates.
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Ensembles with as many as 10,000 cells are used to simulate population synchronization and to compute transient number distributions from asynchronous initial cellstates.
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We sequenced 24,985 Hydra single- cell transcriptomes and identified the molecular signatures of a broad spectrum of cellstates, from stem cells to terminally differentiated cells.