Previous trials in sepsis suggest beneficial effects of levocarnitine on patient- centered outcomes.

Further trials should use uniform assessment criteria and long-term patient- centered outcomes.

These gaps in knowledge can be addressed by comparative effectiveness and patient- centered outcomes research.

The impact of kidney function on patient- centered outcomes in COPD has not been evaluated.

Secondary outcomes will include key patient- centered outcomes, including quality-of-life, physical and social functioning, mood, and treatment satisfaction.

Balanced crystalloids may improve patient- centered outcomes and should be considered as an alternative to normal saline, if available.

Further work is necessary in the investigation of the effect of neuronavigation on operative time, cost, and patient- centered outcomes.

Evoked immune responses were regressed against patient- centered outcomes, contributing to protracted recovery including functional impairment, postoperative pain, and fatigue.

Importance: New models of health care delivery for dermatological care have the potential to increase access and improve patient- centered outcomes.

Objective: To evaluate the learning curve of robotic hysterectomy using objective, patient- centered outcomes and analytic methods proposed in the literature.

Conclusion: These data show that CKD is a relevant comorbidity in COPD patients which impacts on patient- centered outcomes and mortality.

Objectives: Quality of life and psychological well-being are important patient- centered outcomes, which are useful in evaluation of cancer care delivery.

Restricted cubic spline models were used to evaluate a nonlinear relationship between eGFR with patient- centered outcomes, cox survival analysis was applied to evaluate mortality.

Consequently, these findings suggest the need to consider xerostomia in the development of SS classification criteria and in patient- centered outcomes research in SS intervention trials.

Data from this study may be used to design sufficiently powered prospective studies comparing patient- centered outcomes for video laryngoscopy versus direct laryngoscopy during endotracheal intubation.

Aim: The Patient- Centered Outcomes Research Institute Pipeline to Proposal (P2P) Awards Initiative funded 177 awardees to engage patients and stakeholder partners in preresearch.