Significats de chimeric viruses en anglès

Replication-competent chimeric viruses can be constructed by inserting foreign antigenic sequences within the poliovirus polyprotein.

Replication-competent chimeric viruses can be constructed by fusing foreign antigenic sequences to several positions within the poliovirus polyprotein.

To investigate the mechanisms underlying arenavirus nAb evasion we engineered several arenavirus envelope- chimeric viruses and glycan-deficient variants thereof.

Initial studies using chimeric viruses demonstrated that genetic elements within the nonstructural and structural coding regions contributed to AR86 neurovirulence.

The presented data show that tests in mice solely might not be a sufficient model for safety testing of chimeric viruses.

They're creating chimeric viruses from several proteins fused together, and they're emptying out viral envelopes or engineering nanoparticles to provoke immunity in unfamiliar ways.

Molecular cloning, sequencing, construction of chimeric viruses and testing of their oncogenic capacities revealed that both oncogenes of td359 are mutated and biologically defective.

A total of 20 chimeric viruses were constructed and evaluated in vitro, in 1-day-old chicks, and in 2-week-old chickens.

Moreover, this protocol details a robust and reproducible method for assessing the replication capacity of the Gag-MJ4 chimeric viruses on a CEM-based T cell line.