Significats de cognate antigen en anglès

Wild-type cytotoxic T lymphocytes persisted even after the cognate antigen was no longer present.

N-glycans were found to severely impair BCR specificity and affinity to the initial cognate antigen.

However, little is known about the functional consequences of these frequent T cell-DC interactions without cognate antigen.

Following intramuscular administration of β-propiolactone-inactivated rabies virus particles, mice elicited specific immune responses against the cognate antigen.

We also quantify the probability that an auto-reactive thymocyte exits the thymus before it encounters a cognate antigen.

Here, we investigated the effect of N-linked variable-region glycosylation for BCR interaction with cognate antigen and with lectins of different origins.

The interaction between T cells and APCs bearing cognate antigen results in the formation of an immunological synapse (IS).

Naive T cells expressed little T-bet, but this transcription factor was induced markedly by the combination of IFN-gamma and cognate antigen.

Here, we asked how human cognate antigen-responsive CD8+ T cells and their receptors could be identified in unselected single-cell gene expression data.

Presentation of cognate antigen by either graft endothelial cells or bone marrow-derived APCs that extend into the capillary lumen was sufficient for T cell migration.

These observations suggest that receptor revision is a mechanism for receptor diversification that is turned off when antigen receptors are cross-linked by the cognate antigen.

The antibodies that performed best at discriminating disease status were selected, and their cognate antigens were identified using a functional protein microarray.