Significats de complex v en anglès

Here, we present two siblings with a severe neonatal encephalopathy caused by complex V deficiency.

Immunoblotting techniques were applied to study complex V assembly.

Selectivity arises because mitochondria of Pten-null cells consume ATP through complex V, instead of producing it.

All mutations were associated with almost-normal complex V activity but significant oxidative stress and permanent plasma membrane depolarization.

No correlation was found between the degree of complex V enzyme deficiency and the severity of the phenotype.

Decreases in the levels of several mitochondrial proteins (subunits of complex I, complex V, and of the pyruvate dehydrogenase complex) were observed.

In 9 out of 11 patients a decreased ATP production was detected, and complex V activity was deficient in all children.

The in-gel activity assay in the patient's muscle confirmed a combined defect of OXPHOS, particularly indicating suppression of mitochondrial ATP synthase ( complex V) activity.

F0F1-ATP synthase, a complex V of the electron transport chain, is an important constituent of mitochondria-dependent signaling pathways involved in apoptosis.

EPICAT significantly increased complex I expression in AA-treated cells, and 1.0 μM EPICAT significantly decreased mitochondrial complex V expression in HG-treated cells.