Significats de cortical granule en anglès

Results: Many of the unfertilized eggs were in metaphase and had relatively low cortical granule densities indicative of cortical granule loss.

To identify factors that influence the activity of separase in cortical granule exocytosis and cytokinesis, we carried out a genetic suppressor screen.

Newly fertilized mutant embryos have defects in polar body extrusion, fail to undergo cortical granule exocytosis, and subsequently fail to complete cytokinesis.

Conclusion: The observed changes in ZP biochemistry and cortical granule quantitation demonstrate that failed fertilization is frequently associated with spontaneous cytoplasmic, but not nuclear, activation.

Objective: To determine the extent of biochemical changes in the zona pellucida (ZP) and cortical granule release in eggs failing to fertilize in IVF.

The relationship of changes in the ZP and cortical granules to infertility and in vitro culture requires further investigation.