Encara no tenim significats per a "created mice".
1Therefore, we created mice in which MHC class II is expressed only on T lineage cells.
2Using Crispr to delete different critical tissue genes, they created mice without the ability to make a heart, a pancreas, or eyes.
3Previously, we created mice that are unable to synthesize NE and epinephrine due to targeted disruption of the dopamine-beta-hydroxylase gene (Dbh).
4By bone marrow transplantation, we created mice deficient for Cd40 either in the blood compartment but not in the endothelium, or vice versa.
5We have created mice with a targeted deletion of IP6K1 in which production of inositol pyrophosphates is markedly diminished.
6To examine genetic variation of AR in cancer, we created mice by germ-line gene targeting in which human AR sequence replaces that of the mouse.
7We created mice doubly deficient in Cd40 and Cd154 (Dbl KO) and found them to be both fertile and viable.
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