Significats de cytoplasmic localization en anglès

Consistent with a cytoplasmic localization, the biological effects of HDAC6 inhibition appear transcription-independent.

A calcium binding property was found as well as heat stability and cytoplasmic localization.

Hyperphosphorylated forms and cytoplasmic localization of nucleolin both prevail in early embryos up to the midblastula transition.

Subcellular localization analyses confirmed the low level and abnormal cytoplasmic localization of ATM for most A-T cell lines.

The cytoplasmic localization persisted during the complete cell cycle, whereas the nuclear signal disappeared at nuclear envelope breakdown.

We focused on Lrrc75a-as1 and elucidated its transcript structure and confirmed its cytoplasmic localization.

In vivo treatment of MS-444 inhibited HuR cytoplasmic localization and decreased COX-2 expression in tumors.

In addition, we demonstrated that most missense mutations lead to an abnormal cytoplasmic localization of ATM, correlated with its decreased expression.

Recombinant mutant ILK expressed in H9c2 rat myoblast cells shows aberrant prominent cytoplasmic localization compared to the wild-type.

Results: Our results show that DKC1 encodes a new alternatively spliced mRNA able to direct the synthesis of a variant dyskerin with unexpected cytoplasmic localization.

While NP stability and polymerase activity are little affected by sumoylation, the NP sumoylation-defective WSN-NPK4,7R virus exhibited early cytoplasmic localization of NP.

We propose that the observed cytoplasmic localization of Cyclin B1 during interphase reflects the equilibrium between ongoing nuclear import and rapid CRM1-mediated export.